Long-acting GLP-2 analogue

Glucagon-like peptide-2 (GLP-2) is a 33 amino acid peptide that is co-secreted with GLP-1 from the human intestine upon food intake. GLP-2 stimulates intestinal growth and has therapeutic relevance for treatment of inflammatory bowel diseases and short bowel syndrome.

NNC0103-0147 is a protracted GLP-2 analogue that has been characterised for its ability to cross membranes. We have limited data on this specific compound, see the Trier et al. 2014 reference listed in the reference section.