Specialist/Principal Scientist Genome Engineering and Automation

Are you excited about pioneering genome editing technologies for stem cell applications? Do you have expertise in molecular biology, genome editing, stem cell biology, and automated lab robotics? Most importantly, do you thrive in a culture of collaboration, curiosity, and innovation?
If this sounds like you, then we have an incredible opportunity for you! Join the newly established GEM CELL Hub (Genome Engineering & Manufacturing of Stem Cell-Derived Cell Types) within the Global Research Technologies unit. Apply today and take on the exciting challenge of shaping this area and advancing cutting-edge genome editing technologies for stem cell applications. 

The position
As the Principal Scientist, you will be based in Måløv, Denmark and report to the Project Director of the GEM CELL Hub. Your primary responsibility will be to lead the design, execution and analysis of genome engineering experiments of human pluripotent stem cells and their derivatives. This will involve taking part in building and guiding a growing team of scientists and technicians, as well as leveraging the knowledge base from across the organization into the project. You will play a key role in enabling accelerated drug target discovery and screening in early-stage research. You will engage with a wide range of cross-organizational stakeholders in a global setting to maintain an updated and aligned strategy for this dynamic area. 

The main responsibilities can be summarized as follows:  

• Design, develop and optimize genome editing tools and techniques for precise manipulation of the human genome
• Train and mentor a team of scientists and technicians
• Contribute to the strategic direction of the genome engineering program within the GEM CELL Hub, identifying key technologies and approaches to advance the field
• Work closely with cross-functional teams within the GEM CELL Hub and other genome editing groups across Research & Early Development
• Develop and implement novel methodologies for the generation, characterization and application of stem cell-derived models for drug discovery projects using automated lab robotics
• Stay abreast of the latest scientific advancements in the field of genome engineering and intellectual property

The seniority level of the position will be decided based on the chosen candidates’ qualifications and experience. We welcome candidates of all experience levels to apply and grow with us.

Qualifications
To thrive and succeed in the role, you should have:

• A Ph.D. in Molecular Biology, Genetics, Stem Cell Biology, or a related field
• Profound experience in genome engineering, preferably in the industrial setting, with a focus on human pluripotent stem cells and related applications
• Proven track record of applying genome editing tools such as CRISPR/Cas9, TALENs, base editing, or other emerging technologies to stem cell research. Familiarity with automated liquid handling systems and robotics will be considered an advantage
• Demonstrated leadership experience, including managing research teams and guiding scientific strategy 
• Strong record of scientific publications in the field of genome engineering and stem cell biology

As a person, you are curious and driven. You take initiative and have a can-do attitude with the ability to execute a plan and keep deadlines.  You thrive in a changing and dynamic work environment and are skilled in balancing innovative ideas and the focus on key deliverables. You are a good team player, who consistently engages in constructive collaborations and values partnership and knowledge sharing. Your passion for science and ability to impact and progress projects inspires those around you.

About the area
The GEM CELL Hub is based in Bioprocess Research, Global Research Technologies, representing a new effort to bolster our drug discovery program using stem cell-derived cell types for target discovery and drug screening and related purposes. The primary aim is to ensure the accessibility of top-tier stem cell-derived cells for diverse applications, catering to varying demands for cell types and quantities, thereby also requiring the need for ongoing research and development of methods and processes. Ultimately, the goal is to facilitate the distribution of cells to stakeholders across the globe. The project will benefit from the synergies of being co-localized with our cultivation experts in the area while having easy access to assay development colleagues and experts from our therapeutic stem cell area.

Working at Novo Nordisk
At Novo Nordisk, we do not wait for change. We drive it. We are a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence, without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development to manufacturing, marketing, and sales – we’re all working to move the needle on patient care.

Contact
For further information, please contact Charis Segeritz-Walko, Director for GEM CELL Hub at +45 30798169.

Deadline
5 January 2025.

Applications will be reviewed on an ongoing basis, so we encourage you to apply as soon as possible. You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo to your CV.
 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.