Chemical Engineer

Are you passionate about designing and optimizing synthetic routes for active pharmaceutical ingredients? Do you have experience in mechanistic modeling and process design? 
 

We are looking for a Chemical/Process Engineer to join our team in CMC API Development at Novo Nordisk. If you are ready to shape the future of bioprocessing and make a difference in the pharmaceutical industry, read on and apply today for a life-changing career.

Get introduced to CMC Chemical Development and meet our employees by visiting our  career site.

The position
As a Chemical Engineer at Novo Nordisk, you will be instrumental in designing and optimizing synthetic routes for the active pharmaceutical ingredients. You will work closely with a diverse team of chemists, engineers and analytical scientists to ensure robust drug substance manufacture.

Furthermore, your main responsibilities will include:

• Developing mechanistic models for chemical steps such as reaction, filtration and distillation.
• Designing and evaluating experimental kinetic studies of different reactions to provide safe, efficient, robust and scalable processes.
• Supporting late-stage development activities, such as control strategy, Fate & Purge study, PAR.
• Supporting technology transfer to manufacturing sites and process scale-up activities.
• Exploring efficient algorithms for parameter fitting and implementing model-design of experiments.
• Supporting lab-based activities. 

This job gives you a great opportunity to play a part in shaping the future of bioprocessing in close collaboration with development, production, and research teams at Novo Nordisk.
 

Qualifications
To be successful in this role, you should have
 

Essential Skills:

• A MSc or PhD in chemical engineering or similar subject area.
• Good knowledge of the science behind process models and broad modelling experience across API pharmaceutical manufacturing platforms and unit operations.
• Experience in relevant modeling software e.g. Aspen Plus, Matlab, Python, gPROMS.
• Knowledge in reaction engineering, especially reaction kinetics, reactor design, multi-phase reaction systems and thermodynamics. 
• Excellent communication skills and ability to present complex results in a clear and concise manner.
• Ability to work independently and as part of a team, contributing to a collaborative and supportive work environment.

Desirable Skills:

• Experience with chemical process development scale-up and/or technical transfer.
• 2-5 years of experience in the life science industry, preferably in process development and scale-up.
• Knowledge of analytical techniques for protein analysis.

About the department
As part of the Novo Nordisk PSQIT organisation, Chemistry, Manufacturing and Control (CMC) Development & Scaling makes a real difference for patients with chronic diseases across the world. We develop, manufacture, and distribute drug candidates for clinical trials and have a strong culture with a “can do” mindset.
The job is placed in CMC API Development located in Bagsværd. Our main responsibility is to develop manufacturing processes for new proteins and peptides in close collaboration with the research and manufacturing units (clinical and market). You will be part of the late stage-team at Chemical Development, dedicated to model-based process design in close collaboration with early phase teams and manufacturing sites.

In Chemical Development, we are responsible for developing the synthetic processes required to produce the active pharmaceutical ingredients (APIs) for new and innovative product portfolio. These processes encompass chemical modification of recombinantly-produced proteins, as well as chemical synthesis of peptides and small molecules. The department is involved in early non-clinical projects up to Phase 3 GMP-manufacturing, process validation and transfer to commercial production. The aim is to develop robust, technically feasible and economical processes, whilst minimizing the environmental impact.
 

Working at Novo Nordisk
Novo Nordisk is a leading global healthcare company with a 100-year legacy of driving change to defeat serious chronic diseases. Building on our strong legacy within diabetes, we are growing massively and expanding our commitment, reaching millions around the world and impacting more than 40 million patient lives daily. All of this has made us one of the 20 most valuable companies in the world by market cap. Our success relies on the joint potential and collaboration of our more than 63,000 employees around the world. We recognize the importance of the unique skills and perspectives our people bring to the table, and we work continuously to bring out the best in them. Working at Novo Nordisk, we’re working toward something bigger than ourselves, and it’s a collective effort. Join us! Together, we go further. Together, we’re life changing.
 

Contact
For further information contact Associate Manager Michael Koch Meldgaard at +4534489449.
 

Deadline
15 December 2024

The interviews will be held in January.

You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.